HHV8 a subtype is associated with rapidly evolving classic Kaposi's sarcoma

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Kaposis sarcoma in a Nairobi hospital.

BACKGROUND Kaposi's sarcoma (KS) is associated epidemiologically with HIV infection and a number of countries have reported a dramatic increase in the incidence of KS with the advent of AIDS. Although AIDS is prevalent in Kenya, no studies on the impact of AIDS on the pattern of KS has been carried out. OBJECTIVE To determine any changes in the pattern of KS that might have occurred since the...

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Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8).

The genome of the Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) was mapped with cosmid and phage genomic libraries from the BC-1 cell line. Its nucleotide sequence was determined except for a 3-kb region at the right end of the genome that was refractory to cloning. The BC-1 KSHV genome consists of a 140.5-kb-long unique coding region flanked by multiple G + C-rich 801-bp terminal repeat...

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[Classic Kaposi sarcoma associated with lymphedema following arterial catheterization].

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Treatment of classic Kaposi's sarcoma-associated lymphedema with elastic stockings.

Lymphedema of the lower extremities is a frequent complication of Kaposi's sarcoma (KS). Compressive therapy is the basis of treatment for lymphatic disorders, but to the authors' knowledge, there are no controlled trials to evaluate its effectiveness in KS-related lymphedema. Sixty-five patients with classic KS-associated lymphedema limited to below the knee were studied. Fifty patients receiv...

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KSHV/HHV8-associated lymphomas.

This review looks at the current state of knowledge on primary effusion lymphoma (PEL) and other Kaposi sarcoma herpesvirus (KSHV)/human herpesvirus 8 (HHV8)-associated lymphomas. In 1995, KSHV DNA sequences were identified within a distinct subgroup of acquired immunodeficiency syndrome-related non-Hodgkin lymphomas localized in body cavities and presenting as pleural, peritoneal and pericardi...

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ژورنال

عنوان ژورنال: Journal of Medical Virology

سال: 2008

ISSN: 0146-6615,1096-9071

DOI: 10.1002/jmv.21322